4-Methoxy-3-methylbenzoic Acid → 4-methoxy-3-methyl-N-(2-methylheptan-4-yl)benzamide

Participants

Reaction Steps

Prepared in a similar manner as described in example 4 using 4-methoxy-3-methylbenzoic acid and 2-methyl-4-heptanamine (example 2a). Yield: 45%. 1H NMR (500 MHz, CDCl3): δ 0.93 (m, 9H); 1.39 (m, 5H); 1.53 (m, 1H); 1.67 (m, 1H); 2.24 (s, 3H); 3.86 (s, 3H); 4.23 (m, 1H); 5.64 (d, 1H); 6.82 (d, 1H); 7.54 (s, 1H); 7.61 (d, 1H). MS (278, M+H).

Provenance & Evidence