3-Chloro-p-anisic acid → HCID 29322049, compound

HRID 339354Notes

Reaction equation

[C:1]1([C@H:7]([NH2:9])[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:10][C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[C:14](O)=[O:15]>>[Cl:10][C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[C:14]([NH:9][C@@H:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[CH3:8])=[O:15]

Participants

Reactant 2

HCID 1699823-Chloro-p-anisic acid

HCID 6431891-Phenethylamine, (+)-

Product 1

HCID 29322049HCID 29322049, compound

Procedure

Prepare in a similar manner to example 4 using (R)-1-phenylethanamine and 3-chloro-4-methoxy benzoic acid. MS (M+H, 290.0).

Sources & evidence

ORD record: ord-7919262d476a498295060651fbdd4b75
Source dataset: uspto-grants-2014_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08895050B2

Reaction notes

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