3,5-Dimethyl-p-anisic acid → 4-methoxy-3,5-dimethyl-N-(2-methylheptan-4-yl)benzamide

HRID 339358Notes

Reaction equation

HRID 339358 reaction equation
[CH3:1][O:2][C:3]1[C:11]([CH3:12])=[CH:10][C:6]([C:7]([OH:9])=O)=[CH:5][C:4]=1[CH3:13].[CH3:14][CH:15]([CH2:17][CH:18]([NH2:22])[CH2:19][CH2:20][CH3:21])[CH3:16]>>[CH3:1][O:2][C:3]1[C:4]([CH3:13])=[CH:5][C:6]([C:7]([NH:22][CH:18]([CH2:19][CH2:20][CH3:21])[CH2:17][CH:15]([CH3:16])[CH3:14])=[O:9])=[CH:10][C:11]=1[CH3:12]

Participants

3

Reactant 2

HCID 889443,5-Dimethyl-p-anisic acidHCID 144181752-Methylheptan-4-amine

Product 1

HCID 575278964-methoxy-3,5-dimethyl-N-(2-methylheptan-4-yl)benzamide

Procedure

Prepared in a similar manner to example 4 using 4-methoxy-3,5-dimethylbenzoic acid and 2-methylheptan-4-amine (example 2a). MS (M+H, 292.2).

Sources & evidence

ORD record
ord-f99fa67e0da94336bf590a5718065c78
Source dataset
uspto-grants-2014_11
Patent number
US08895050B2

Reaction notes

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