4-Heptanamine → N-(heptan-4-yl)benzofuran-5-carboxamide

HRID 339377Notes

Reaction equation

[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[CH:3]=[CH:2]1.[CH3:13][CH2:14][CH2:15][CH:16]([NH2:20])[CH2:17][CH2:18][CH3:19]>>[CH3:13][CH2:14][CH2:15][CH:16]([NH:20][C:10]([C:8]1[CH:7]=[CH:6][C:5]2[O:1][CH:2]=[CH:3][C:4]=2[CH:9]=1)=[O:12])[CH2:17][CH2:18][CH3:19]

Participants

Reactant 2

HCID 386654-Heptanamine

HCID 5956561-Benzofuran-5-Carboxylic Acid

Product 1

HCID 57527783N-(heptan-4-yl)benzofuran-5-carboxamideYield 41%

Procedure

Prepared in a similar manner to example 4 using benzofuran-5-carboxylic acid and heptan-4-amine. Yield 41%. MS (M+H, 260.2).

Sources & evidence

ORD record: ord-28439206352e4399bad98b8612d33836
Source dataset: uspto-grants-2014_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08895050B2

Reaction notes

Loading…