2-Thiophenecarboxylic acid → HCID 18130179, compound
Reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([OH:8])=O.[F:9][C:10]([F:21])([F:20])[O:11][C:12]1[CH:17]=[CH:16][C:15]([CH2:18][NH2:19])=[CH:14][CH:13]=1>>[F:9][C:10]([F:20])([F:21])[O:11][C:12]1[CH:17]=[CH:16][C:15]([CH2:18][NH:19][C:6]([C:2]2[S:1][CH:5]=[CH:4][CH:3]=2)=[O:8])=[CH:14][CH:13]=1Participants
3
Procedure
Prepared in a similar manner as described in example 4 from thiophene-2-carboxylic acid and (4-(trifluoromethoxy)phenyl)methanamine. MS (M+H, 303).
Workup
- customPrepared in a similar manner
Sources & evidence
- ORD record
- ord-3654583ad8fb49e98b368b59186f233c
- Source dataset
- uspto-grants-2014_11
- Patent number
- US08895050B2
Reaction notes
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