2,4-Dimethoxybenzylamine → 5-Pyridin-2-yl-thiophene-2-carboxylic Acid 2,4-dimethoxy-benzylamide

HRID 339389Notes

Reaction equation

HRID 339389 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[S:11][C:10]([C:12]([OH:14])=O)=[CH:9][CH:8]=1.[CH3:15][O:16][C:17]1[CH:24]=[C:23]([O:25][CH3:26])[CH:22]=[CH:21][C:18]=1[CH2:19][NH2:20]>>[CH3:15][O:16][C:17]1[CH:24]=[C:23]([O:25][CH3:26])[CH:22]=[CH:21][C:18]=1[CH2:19][NH:20][C:12]([C:10]1[S:11][C:7]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)=[CH:8][CH:9]=1)=[O:14]

Participants

3

Reactant 2

HCID 5972502,4-DimethoxybenzylamineHCID 7364825-(Pyridin-2-yl)thiophene-2-carboxylic acid

Product 1

HCID 575279155-Pyridin-2-yl-thiophene-2-carboxylic Acid 2,4-dimethoxy-benzylamide

Procedure

Prepared in a similar manner to example 4 using 5-pyridin-2-yl-thiophene-2-carboxylic acid and 2,4-dimethoxy-benzylamine. MS (M+H, 355.2).

Sources & evidence

ORD record
ord-f5ccf7b6f94c4a9c8f6eecbfdfb39f6f
Source dataset
uspto-grants-2014_11
Patent number
US08895050B2

Reaction notes

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