1,3-Benzodioxole-5-carboxylic acid → Benzo[1,3]dioxole-5-carboxylic Acid [2-(4-ethyl-phenyl)-ethyl]-amide

HRID 339392Notes

Reaction equation

[O:1]1[C:5]2[CH:6]=[CH:7][C:8]([C:10]([OH:12])=O)=[CH:9][C:4]=2[O:3][CH2:2]1.[CH2:13]([C:15]1[CH:20]=[CH:19][C:18]([CH2:21][CH2:22][NH2:23])=[CH:17][CH:16]=1)[CH3:14]>>[CH2:13]([C:15]1[CH:20]=[CH:19][C:18]([CH2:21][CH2:22][NH:23][C:10]([C:8]2[CH:7]=[CH:6][C:5]3[O:1][CH2:2][O:3][C:4]=3[CH:9]=2)=[O:12])=[CH:17][CH:16]=1)[CH3:14]

Participants

Reactant 2

HCID 71961,3-Benzodioxole-5-carboxylic acid

HCID 1440474-Ethylphenethylamine

Product 1

HCID 57527901Benzo[1,3]dioxole-5-carboxylic Acid [2-(4-ethyl-phenyl)-ethyl]-amide

Procedure

Prepared in a similar manner to example 4 using benzo[1,3]dioxole-5-carboxylic acid and 2-(4-ethyl-phenyl)-ethylamine. MS (M+H, 298.2).

Sources & evidence

ORD record: ord-cf29219fee854662810c9566bcd31da8
Source dataset: uspto-grants-2014_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08895050B2

Reaction notes

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