Diisopropyl Ether → HCID 86681580, compound

Participants

Reaction Conditions

Reaction Steps

0.77 g (1.9 mmol) of Lawesson's reagent was added, at room temperature, to a tetrahydrofuran (8 ml) solution containing 0.40 g (1.6 mmol) of 1-(2-carbamoyl-2-isopropoxyimino-1-methoxyiminoethyl)-1H-1,2,4-triazole, followed by stirring at 40° C. for 2 hours and then at 60° C. for 3 hours. The reaction mixture was cooled to room temperature. Thereto was added diisopropyl ether. The mixture was washed with water and an aqueous saturated sodium chloride solution and dried over anhydrous sodium sulfate. The solvent was distilled off. The resulting residue was purified by silica gel column chromatography (elutant:ethyl acetate/hexane=1/2) to obtain 0.25 g (yield: 58%) of a title compound as a yellow powder.

Provenance & Evidence