1,2-Dichloroethane → HCID 86681582, compound

Participants

Reaction Steps

To 8 ml of 1,2-dichloroethane was added 7.5 ml (7.5 mmol) of a trimethylaluminum (1 mol/l) hexane solution. Thereinto was drop-wise added 0.47 g (7.5 mmol) of ethanethiol at room temperature, followed by stirring for 30 minutes. To this mixed solution was added, at room temperature, a 1,2-dichloroethane solution containing 0.50 g (1.9 mmol) of the 1-(2-isopropoxyimino-2-methoxycarbonyl-1-methoxyiminoethyl)-1H-1,2,4-triazole produced in Example 12, followed by stirring for 1.5 hours. The reaction mixture was diluted with isopropyl ether. Thereto was added a small amount of water, followed by stirring. The resulting precipitate was removed by filtration. The solvent was distilled off. The resulting residue was purified by silica gel column chromatography (elutant:ethyl acetate/hexane=1/2) to obtain 0.56 g (yield: 98%) of a title compound as a yellow oily matter.

Provenance & Evidence