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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 339441Generated: October 25, 2026

L-Phenylalanine → (3S)-3-amino-3-phenylpropanoic acid

https://huagongshe.com/reaction/339441

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-PhenylalanineHCID 6140—
ReactantAzane;hydrateHCID 12896473—
SolventWaterHCID 962—
Product(3S)-3-amino-3-phenylpropanoic acidHCID 686704—

Reaction Steps

The reaction solution (250 g) containing 12 weight % (wt %) of L-phenylalanine, a bacterial cell (in an appropriate amount) of MT-11046 produced in Example 1 and water was reacted at 25 degrees centigrade for 24 hours or more. During the reaction, pH of the reaction solution was adjusted to each pH shown in Table 1 with 25% ammonia water. A solid of (S)-β-phenylalanine precipitated under all examined conditions was observed. The reaction yields of (S)-β-phenylalanine in respective pHs are shown in Table 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08895270B2
Source datasetuspto-grants-2014_11
ORD IDord-d5f944b54e944e4cb09dfadf1ea7fc92
Source noteuspto-grants-2014_11