化工社化工社 化学情報印刷レポート · 研究参考用
Stannous chloride dihydrate → 4-(1,3-Benzothiazol-2-yl)-3-methoxyaniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Stannous chloride dihydrate | HCID 61436 | — |
| 反応物 | Tetrahydrofuran hexane | HCID 21883165 | — |
| 反応物 | 2-(2-Methoxy-4-nitrophenyl)benzothiazole | HCID 67237280 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 4-(1,3-Benzothiazol-2-yl)-3-methoxyaniline | HCID 67236876 | 96% |
反応手順
Prepared as described in the Nitro Reduction section using 2-(2-methoxy-4-nitrophenyl)benzothiazole (0.1 g, 0.35 mmol) and tin (II) dichloride dihydrate (0.63 g, 2.8 mmol) in EtOH (12 ml) to give the title compound (0.086 g, 96%) as a pale orange solid after work-up and flash chromatography (2:1 Hexane/THF).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08895313B2 |
| 出典データセット | uspto-grants-2014_11 |
| ORD ID | ord-dbbd9d4103324bac9695dc404b6b5456 |
| 出典メモ | uspto-grants-2014_11 |