HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → 4-(6-Methoxy-1,3-benzothiazol-2-yl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | 6-Methoxy-2-(4-nitrophenyl) benzothiazole | HCID 10660852 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-(6-Methoxy-1,3-benzothiazol-2-yl)aniline | HCID 391870 | 93.6% |
Reaction Steps
Prepared as described in the Nitro Reduction section using 2-(4-nitrophenyl)-6-methoxybenzothiazole (5.0 g, 17.5 mmol) and tin (II) dichloride dihydrate (31.5 g, 0.14 mol) in EtOH (150 ml) to give the title compound (4.2 g, 93%) as a colourless solid after work-up and recrystallisation from EtOH.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08895313B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-15f369d2d1e442018b37cb1474605b38 |
| Source note | uspto-grants-2014_11 |