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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 339524Generated: October 30, 2026

Stannous chloride dihydrate → HCID 67312218, compound

https://huagongshe.com/reaction/339524

Reaction equation

Participants

RoleNameHCIDCharge
ReactantStannous chloride dihydrateHCID 61436—
ReactantEthyl acetate hexaneHCID 21226206—
ReactantHCID 67311687HCID 67311687—
SolventEthanolHCID 702—
ProductHCID 67312218HCID 6731221873.1%

Reaction Steps

Prepared as described in the Nitro Reduction section using 4-nitro-3-trifluoromethyl-N-[4-(6-methoxybenzothiazol-2-yl)-phenyl]-benzamide (0.35 g, 0.74 mmol) and tin (II) chloride dihydrate (1.33 g, 5.91 mmol) in EtOH (7 ml) to give the title compound (0.24 g, 73%) as a pale yellow solid after work-up and flash chromatography (3:2 Hexane/EtOAc).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08895313B2
Source datasetuspto-grants-2014_11
ORD IDord-c19de5d158c745dea8791b7acf088282
Source noteuspto-grants-2014_11