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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 339541Generated: October 29, 2026

Dehydrothio-4-toluidine → HCID 733129, compound

https://huagongshe.com/reaction/339541

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDehydrothio-4-toluidineHCID 7087—
ReactantBenzoyl chlorideHCID 7412—
ReactantTriethylamineHCID 8471—
SolventTetrahydrofuranHCID 8028—
ProductHCID 733129HCID 73312986%

Reaction Steps

Prepared as described in the Amide Coupling section using 2-(4-aminophenyl)-6-methylbenzothiazole (1.0 g, 4.16 mmol) and benzoyl chloride (0.58 g, 4.16 mmol) in dry THF (10 ml) containing triethylamine (0.46 g, 4.58 mmol) to give the title compound (1.23 g, 86%) as a colourless solid after work-up.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08895313B2
Source datasetuspto-grants-2014_11
ORD IDord-31a90c4be840436398e42332805561be
Source noteuspto-grants-2014_11