Formaldehyde → HCID 5194646, compound

Participants

Reaction Steps

Prepared as described in the Amination section using sodium cyanoborohydride (0.44 g, 6.95 mmol), 3-amino-N-[4-(6-methyl benzothiazol-2-yl)-phenyl]-benzamide (0.50 g, 1.39 mmol) and paraformaldehyde (0.42 g, 13.9 mmol) in AcOH (8 ml) to give the title compound (0.15 g, 28%) as a colourless solid after work-up and flash chromatography (2:1 Hexane/EtOAc).

Provenance & Evidence