HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → HCID 28325551, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | Imidazo[2,1-b]thiazole, 3-methyl-6-(4-nitrophenyl)- | HCID 3926234 | — |
| Reactant | Dichloromethane ethylacetate | HCID 21226138 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 28325551 | HCID 28325551 | 50% |
Reaction Steps
Prepared as described in the Nitro Reduction section using 3-methyl-6-(4-nitrophenyl)imidazo[2,1-b][1,3]thiazole (0.20 g, 0.772 mmol) and tin (II) chloride dihydrate (0.87 g, 3.86 mmol) in EtOH (20 ml) to give the title compound (88 mg, 50%) as a pale orange solid after work-up and flash chromatography (1:1 DCM/EtOAc).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08895313B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-1ff2bf52fdab410c9bc87904e6a21177 |
| Source note | uspto-grants-2014_11 |