2-Aminopyrimidine → HCID 67236960, compound

Participants

Reaction Steps

A mixture of 2-aminopyrimidine (0.40 g, 4.22 mmol) and 2-bromo-4′-nitroacetophenone (1.03 g, 4.22 mmol) in DMF (8 ml) was stirred at rt for 16 h. EtOAc (15 ml) was added to the resulting yellow, viscous mixture and the precipitate collected by filtration and washed with EtOAc (50 ml). After drying under high vacuum, a yellow solid was obtained (0.67 g, 51%).

Provenance & Evidence