HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → HCID 23106705, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | Dichloromethane ethylacetate | HCID 21226138 | — |
| Reactant | HCID 23106531 | HCID 23106531 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 23106705 | HCID 23106705 | 82% |
Reaction Steps
Prepared as described in the Nitro Reduction section using 6-fluoro-2-(4-nitrophenyl)imidazo[1,2-a]pyridine (0.45 g, 1.75 mmol) and tin (II) dichloride dihydrate (1.97 g, 8.75 mmol) in EtOH (25 ml) to give the title compound (0.325 g, 82%) as a pale yellow solid after work-up and flash chromatography (4:1 EtOAc/DCM).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08895313B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-9bece5b368a54a7caa8cae4e08d1934f |
| Source note | uspto-grants-2014_11 |