HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(6-Methylimidazo[1,2-a]pyridin-2-yl)aniline → HCID 58342020, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(6-Methylimidazo[1,2-a]pyridin-2-yl)aniline | HCID 821084 | — |
| Reactant | 4-Methoxy-3-(trifluoromethyl)benzoyl chloride | HCID 2775298 | — |
| Reactant | Ethyl acetate hexane | HCID 21226206 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 58342020 | HCID 58342020 | 38.5% |
Reaction Steps
Prepared as described in the Amide Coupling section using 4-(6-methylimidazo[1,2-a]pyridin-2-yl)aniline (0.20 g, 0.897 mmol) and 4-methoxy-3-trifluoromethylbenzoyl chloride (0.21 g, 0.897 mmol) in dry pyridine (15 ml) to give the title compound as a colourless solid (0.147 g, 38%) after work-up and flash chromatography (15:1 EtOAc/Hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08895313B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-ab14ba6b8cf7402ab8aa7f67062beae0 |
| Source note | uspto-grants-2014_11 |