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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 339576Generated: October 30, 2026

4-(Dimethylamino)benzoyl chloride → HCID 58342138, compound

https://huagongshe.com/reaction/339576

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Dimethylamino)benzoyl chlorideHCID 4400782—
ReactantDichloromethane ethylacetateHCID 21226138—
ReactantHCID 23106705HCID 23106705—
SolventPyridineHCID 1049—
ProductHCID 58342138HCID 5834213836%

Reaction Steps

Prepared as described in the Amide Coupling section using 4-(6-fluoroimidazo[1,2-a]pyridin-2-yl)aniline (100 mg, 0.44 mmol) and 4-dimethylaminobenzoyl chloride (81 mg, 0.44 mmol) in dry pyridine (5 ml) to give the title compound (59 mg, 36%) as a pale yellow solid after work-up and flash chromatography (1:1 DCM/EtOAc).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08895313B2
Source datasetuspto-grants-2014_11
ORD IDord-0eaad7b47f8145db94cc53c2176a9eea
Source noteuspto-grants-2014_11