HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Dimethylamino)benzoyl chloride → HCID 58342138, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Dimethylamino)benzoyl chloride | HCID 4400782 | — |
| Reactant | Dichloromethane ethylacetate | HCID 21226138 | — |
| Reactant | HCID 23106705 | HCID 23106705 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 58342138 | HCID 58342138 | 36% |
Reaction Steps
Prepared as described in the Amide Coupling section using 4-(6-fluoroimidazo[1,2-a]pyridin-2-yl)aniline (100 mg, 0.44 mmol) and 4-dimethylaminobenzoyl chloride (81 mg, 0.44 mmol) in dry pyridine (5 ml) to give the title compound (59 mg, 36%) as a pale yellow solid after work-up and flash chromatography (1:1 DCM/EtOAc).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08895313B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-0eaad7b47f8145db94cc53c2176a9eea |
| Source note | uspto-grants-2014_11 |