Ethyl acetate hexane → HCID 136400552, compound

Participants

Reaction Steps

Prepared as described in the Demethylation section above using 6-methoxy-2-(4-{(E)-2-[4-methoxy-2-(trifluoromethyl)phenyl]ethenyl}phenyl)-1,3-benzothiazole (0.30 g, 0.68 mmol) in dry DCM (10 ml) and BBr3 in DCM (1.0 M, 1.40 ml, 1.40 mmol) at −78° C. give the title compound (0.229 g, 81%) as a yellow solid after work-up and flash chromatography (1:1 Hexane/EtOAc).

Provenance & Evidence