HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → 2-{4-[2-(3-Aminophenyl)-vinyl]-phenyl}-6-methylbenzothiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | Dichloromethane ethylacetate | HCID 21226138 | — |
| Reactant | HCID 67238043 | HCID 67238043 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-{4-[2-(3-Aminophenyl)-vinyl]-phenyl}-6-methylbenzothiazole | HCID 67238150 | 71% |
Reaction Steps
Prepared as described in the Nitro Reduction section using 2-{4-[2-(3-nitrophenyl)-vinyl]-phenyl}-6-methylbenzothiazole (0.12 g, 0.322 mmol) and tin (II) chloride dihydrate (0.58 g, 2.58 mmol) in EtOH (3 ml) to give the title compound (0.078 g, 71%) as a pale yellow solid after work-up and flash chromatography (20:1 DCM/EtOAc).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08895313B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-e59db627525b4ecebeed42f93bc0be5e |
| Source note | uspto-grants-2014_11 |