1,3-Benzodioxole-5-ethanamine → HCID 51301950, compound

HRID 339659Notes

Reaction equation

HRID 339659 reaction equation
[CH2:1]1[O:9][C:8]2[CH:7]=[CH:6][C:5]([CH2:10][CH2:11][NH2:12])=[CH:4][C:3]=2[O:2]1.[CH2:13]1[O:21][C:20]2[CH:19]=[CH:18][C:17]([N:22]=[C:23]=[O:24])=[CH:16][C:15]=2[O:14]1>C1C=CC=CC=1>[CH2:13]1[O:21][C:20]2[CH:19]=[CH:18][C:17]([NH:22][C:23]([NH:12][CH2:11][CH2:10][C:5]3[CH:6]=[CH:7][C:8]4[O:9][CH2:1][O:2][C:3]=4[CH:4]=3)=[O:24])=[CH:16][C:15]=2[O:14]1

Participants

4

Reactant 2

HCID 738741,3-Benzodioxole-5-ethanamineHCID 52232135-Isocyanato-1,3-dioxaindane

Product 1

HCID 51301950HCID 51301950, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A solution of 3,4-methylenedioxyphenylethylamine (0.25 g, 1.5 mmol) and 3,4-methylenedioxy-phenyl isocyanate (0.25 g, 1.5 mmol) in benzene (25 ml) was refluxed for 1 hour. The precipitate formed was filtered, washed with benzene then dried to give pure DC-0078B (0.43 g, 85%) as a pale brown solid.

Workup

  1. customThe precipitate formed
  2. filtrationwas filtered
  3. washwashed with benzene
  4. customthen dried
  5. customto give pure DC-0078B (0.43 g, 85%) as a pale brown solid

Sources & evidence

ORD record
ord-466c91cae3ed45d7b4e85c4aff85f674
Source dataset
uspto-grants-2014_11
Patent number
US08895554B2

Reaction notes

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