HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2-Dimethoxypropane → 8-Bromo-2-(2,2-dimethyl-1,3-dioxolan-4-yl)quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2-Dimethoxypropane | HCID 6495 | — |
| Reactant | 1-(8-Bromoquinolin-2-yl)ethane-1,2-diol | HCID 67234514 | — |
| Reactant | Bentonite | HCID 71586775 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 8-Bromo-2-(2,2-dimethyl-1,3-dioxolan-4-yl)quinoline | HCID 67234369 | — |
Reaction Steps
To 1-(8-bromoquinolin-2-yl)ethane-1,2-diol (505 mg, 1.88 mmol) in acetone (5 mL) and 2,2-dimethoxypropane (5 mL, 1.88 mmol) was added Montmorillonite K 10 (1 g). The reaction mixture was stirred for 2 hours, then filtered and concentrated to give crude product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08895550B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-8ae0cdbdbda24f8f9fb12dcb9ae8e45b |
| Source note | uspto-grants-2014_11 |