HRID339894

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC1=NS(=O)(=O)C(C)(c2ccc(C(C)(C)C)cc2)C(C)(C)O1

HCID86705333

未命名化合物

结构：CC1(C)OC(N[C@@H](CCO)c2ccccc2)=NS(=O)(=O)C1(C)c1cccc(Br)c1

HCID178431678

未命名化合物

结构：CC(C)(C)c1ccc(C2(C)C(C)(C)OC(N[C@@H](CCO)c3ccccc3F)=NS2(=O)=O)cc1

HCID178440750

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)c1ccc(C(C)(C(C)(C)O)S(N)(=O)=O)cc1

HCID68292561

未命名化合物

PROCEDURE

实验过程

The further conversion to (S)-3-[5-(4-tert-butylphenyl)-5,6,6-trimethyl-4,4-dioxo-5,6-dihydro-4H-4lambda6-[1,4,3]oxathiazin-2-ylamino]-3-(2-fluorophenyl)propan-1-ol was effected via the 5-(4-tert-butylphenyl)-2-methoxy-5,6,6-trimethyl-5,6-dihydro-1,4,3-oxathiazine 4,4-dioxide intermediate in analogy to the preparation of (S)-3-[5-(3-bromophenyl)-5,6,6-trimethyl-4,4-dioxo-5,6-dihydro-4H-4lambda6-[1,4,3]oxathiazin-2-ylamino]-3-phenylpropan-1-ol.