Methanol → HCID 57384852, compound

HRID 339935Notes

Reaction equation

HRID 339935 reaction equation
[NH2:1][C:2]1[N:10]=[C:9]([O:11][CH2:12][CH2:13][CH2:14][CH3:15])[N:8]=[C:7]2[C:3]=1[NH:4][C:5](=[O:35])[N:6]2[CH2:16][CH2:17][CH2:18][N:19]([CH2:24][C:25]1[CH:30]=[CH:29][C:28]([CH2:31][C:32]([OH:34])=[O:33])=[CH:27][CH:26]=1)[CH2:20][CH2:21][CH2:22][OH:23].[CH3:36]O>Cl[Si](C)(C)C>[NH2:1][C:2]1[N:10]=[C:9]([O:11][CH2:12][CH2:13][CH2:14][CH3:15])[N:8]=[C:7]2[C:3]=1[NH:4][C:5](=[O:35])[N:6]2[CH2:16][CH2:17][CH2:18][N:19]([CH2:24][C:25]1[CH:26]=[CH:27][C:28]([CH2:31][C:32]([O:34][CH3:36])=[O:33])=[CH:29][CH:30]=1)[CH2:20][CH2:21][CH2:22][OH:23]

Participants

4

Reactant 2

HCID 887MethanolHCID 57384595HCID 57384595, compound

Product 1

HCID 57384852HCID 57384852, compound

Reagents, catalysts & solvents 1

HCID 6397ChlorotrimethylsilaneSolvent

Procedure

To the product from step (ii) (0.38 g) in MeOH, chlorotrimethylsilane (3 mL) was added and the mixture stirred at rt for 1 hr. The solvent was removed to give the subtitle compound as a cream solid (0.39 g); MS multimode (+) 501.

Workup

  1. customThe solvent was removed

Sources & evidence

ORD record
ord-58337a0dff5e484a9136274245c65478
Source dataset
uspto-grants-2014_11
Patent number
US08895570B2

Reaction notes

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