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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 340042Generated: October 30, 2026

Pyrrolidine → HCID 178436920, compound

https://huagongshe.com/reaction/340042

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
ReactantHCID 178436919HCID 178436919—
ProductHCID 178436920HCID 17843692021.2%

Reaction Steps

The title compound was prepared from (5-chloropyrazin-2-yl)(2-(6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol-3-yl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (80 mg, 154 μmol) and pyrrolidine (22 mg, 308 μmol) using the method of Example 32. The crude material was purified by HPLC Method D to afford (18 mg, 19%) of the title compound as off-white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08895544B2
Source datasetuspto-grants-2014_11
ORD IDord-80f96c10132c4c519ce5d44b3f3f9e09
Source noteuspto-grants-2014_11