HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → HCID 178436920, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | HCID 178436919 | HCID 178436919 | — |
| Product | HCID 178436920 | HCID 178436920 | 21.2% |
Reaction Steps
The title compound was prepared from (5-chloropyrazin-2-yl)(2-(6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol-3-yl)-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (80 mg, 154 μmol) and pyrrolidine (22 mg, 308 μmol) using the method of Example 32. The crude material was purified by HPLC Method D to afford (18 mg, 19%) of the title compound as off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08895544B2 |
| Source dataset | uspto-grants-2014_11 |
| ORD ID | ord-80f96c10132c4c519ce5d44b3f3f9e09 |
| Source note | uspto-grants-2014_11 |