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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 340482Generated: October 28, 2026

HCID 86683865, compound → HCID 55291136, compound

https://huagongshe.com/reaction/340482

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86683865HCID 86683865—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 55291136HCID 5529113641.4%

Reaction Steps

A methanol (15 ml) solution containing 1-cyclopropyl-5-nitro-1H-imidazole (60 mg) was prepared and subjected to hydrogenation reaction (80° C.; 50 bar; flow rate: 2 ml/min; 10% Pd/C) using H-cube™. Thereafter, the solvent was distilled away under reduced pressure, and a purple solid of 1-cyclopropyl-1H-imidazol-5-amine (20 mg) was thus obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08895585B2
Source datasetuspto-grants-2014_11
ORD IDord-09651068f82b48b383805a768624a669
Source noteuspto-grants-2014_11