Phosphorus oxychloride → 5-chloro-3-naphthalen-2-yl-1H-pyrazolo[4,3-b]pyridine

Participants

Reaction Steps

After treating 210 mg of 3-(naphthalen-2-yl)-1-trityl-1H-pyrazolo[4,3-b]pyridine obtained by Production example 419 in the similar method as described in Production example 4, 2 mL of residue solution in toluene was added at room temperature with 190 μl of phosphorus oxychloride, and treated in the similar method as described in Production example 28, to afford 60 mg of the title compound as a pale yellow powder.

Provenance & Evidence