Acetic Anhydride → 1-(Acetylamino-methyl)-cyclopropane carboxylic acid{6-fluoro-3-[(e)-2-(4-fluorophenyl)-vinyl]-1h-indazol-5-yl}-amide

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To a solution of 10 mg of 1-aminomethyl-cyclopropane carboxylic acid {6-fluoro-3-[(E)-2-(4-fluorophenyl)-vinyl]-1H-indazol-5-yl}-amide obtained by Example 758 in 0.3 mL of N,N-dimethylformamide was added 2.9 mg of acetic anhydride, and stirred at room temperature for 38 hours under nitrogen atmosphere, and separated and purified by LC-MS, to afford 3.66 mg of the title compound.

Provenance & Evidence