反应详情

2,5-Bis(2-fluorophenyl)-2,4-dihydro-3H-pyrazol-3-one [(Example 107, Step 1), 85 mg, 0.31 mmol] and triethylorthoformate (0.057 mL, 0.34 mmol, 1.1 equiv) were combined and placed into a preheated oil bath at 100° C. for 1 hour. The mixture was cooled to ambient temperature and concentrated in vacuo, providing the titled compound.

1. concentrationconcentrated in vacuo