HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 34111Generated: October 25, 2026
Hydrazine hydrate (1:1) → 2-(Piperidin-1-yl)acetohydrazide
https://huagongshe.com/reaction/34111
Participants
| Role | Name | HCID | Charge |
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| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 1-Piperidineacetic acid, ethyl ester | HCID 643466 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-(Piperidin-1-yl)acetohydrazide | HCID 6421769 | — |
Reaction Steps
3.86 g of piperidin-1-yl-acetic acid ethyl ester was dissolved in 40 mL of ethanol, added with 3.39 mL of hydrazine monohydrate, and stirred at 70° C. for 5 hours. After allowing the solution to cool to room temperature, the solvent was evaporated, to afford 3.8 g of the title compound as pale yellow crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07429609B2 |
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| Source dataset | uspto-grants-2008_09 |
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| ORD ID | ord-c7ae76d9cb824d00b70c01074d2b137b |
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| Source note | uspto-grants-2008_09 |
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