HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen chloride-ethyl acetate → N'-methyl(benzyloxy)carbohydrazide hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Reactant | 2-Benzyl 1-tert-butyl 1-methylhydrazine-1,2-dicarboxylate | HCID 45158420 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | N'-methyl(benzyloxy)carbohydrazide hydrochloride | HCID 24801390 | — |
Reaction Steps
17.7 g of N′-benzyloxycarbonyl-N-methyl-hydrazine carboxylic acid tert-butyl ester was dissolved in 20 mL of ethyl acetate, added with 70 mL 4N hydrogen chloride-ethyl acetate solution, and stirred at room temperature for 4 hours. The solvent was evaporated, and the resulting crystals were washed with diethyl ether and filtered, to afford 11.4 g of the title compound as white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07429609B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-c1425efaa5224cce923be8ab8da418f9 |
| Source note | uspto-grants-2008_09 |