Potassium Carbonate → HCID 59320871, compound

Participants

Reaction Steps

A solution of 1-[3-(7-Formyl-imidazo[1,2-a]pyridin-3-yl)-phenyl]-3-(2,2,2-trifluoro-ethyl)-urea (15 mg, 0.04 mmol), potassium carbonate (11 mg, 0.08 mmol) and TosMic (9.7 mg, 0.05 mmol) were heated in MeOH (2 ml) at 80° C. for 3 h. The reaction mixture was purified using a C18 SPE cartridge, washing with water and eluting the desired compound with MeOH. Removal of the solvent in vacuo afforded the title compound (6 mg). MS: [M+H]+=402

Provenance & Evidence