HCID 46186185, compound → HCID 46186186, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 15 (72 mg, 0.17 mmol) in MeOH (1 mL) was added a catalytic amount of Ni Raney. This mixture was stirred overnight at 50° C. under nitrogen atmosphere. The solids were filtered off and the filtrate evaporated to give 16. 1H-NMR (300 MHz, DMSO-d6): δ 8.78 (d, 1H, J=2.4 Hz), 8.60 (d, 1H, J=2.4 Hz), 8.30 (d, 1H, J=8.7 Hz), 8.14 (bs, 1H), 8.04 (d, 1H, J=8.7 Hz); 8.02 (d, 1H, J=7.2 Hz), 7.70 (t, 1H, J=7.2 Hz), 7.59-7.54 (m, 3H), 6.74 (bs, 2H); 3.05 (m, 2H), 2.96 (m, 2H); MS (ESI) m/z 386 [M-NH3+], 386 [M+H+], 408 [M+Na+].

Provenance & Evidence