HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 4-Chloro-6-methyl-7-(2,5-dihydropyrrol-1-yl-carbonyl)-quinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Pyrroline | HCID 66059 | — |
| Reactant | 6-Methyl-4-oxo-3,4-dihydro-quinazoline-7-carboxylic acid | HCID 136363910 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Chloro-6-methyl-7-(2,5-dihydropyrrol-1-yl-carbonyl)-quinazoline | HCID 86632696 | — |
Reaction Steps
Prepared analogously to Example 2b or 2c from 6-methyl-4-oxo-3,4-dihydro-quinazoline-7-carboxylic acid, thionyl chloride, 2,5-dihydropyrrole, sodium hydroxide solution and dichloromethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07429597B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-43e80a9573df46fb99ae35d42496dc0e |
| Source note | uspto-grants-2008_09 |