反应详情

Prepared according to the method described for Intermediate 135 above from 6-Hydroxypyridine-3-carboxylic acid (0.556 g, 4 mmol, thionyl chloride (1.2 mL, 16 mmol) and 4-amino-N-hydroxy-6-[methyl(phenyl)amino]-1,3,5-triazine-2-carboximidamide (prepared in an analogous manner to Intermediate 1, 0.52 g, 2 mmol). Method B HPLC-MS: MH+ requires m/z=363 Found: m/z=363, Rt=1.52 min (87%).

1. customPrepared