Acetic Anhydride → HCID 54147674, compound

HRID 341730Notes

Reaction equation

HRID 341730 reaction equation
[CH3:1][S:2][C:3]1[C:8]([S:9][CH3:10])=[C:7]([Cl:11])[CH:6]=[CH:5][C:4]=1[C:12](=[O:19])[CH2:13][C:14]([CH:16]1[CH2:18][CH2:17]1)=[O:15].[C:20]([O:23][C:24](=O)C)(=O)[CH3:21]>C(O)(=O)C>[CH3:1][S:2][C:3]1[C:8]([S:9][CH3:10])=[C:7]([Cl:11])[CH:6]=[CH:5][C:4]=1[C:12](=[O:19])[C:13](=[CH:24][O:23][CH2:20][CH3:21])[C:14]([CH:16]1[CH2:18][CH2:17]1)=[O:15]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 53782584HCID 53782584, compound

Product 1

HCID 54147674HCID 54147674, compoundYield 100.9%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of 1-[2,3-bis(methylsulphenyl)-4-chlorophenyl]-3-cyclopropylpropan-1,3-dione (3.45 g) and acetic anhydride (3.37 g) in acetic acid was stirred and heated at reflux for 3 hours. It was cooled and evaporated to dryness. The residue was dissolved in toluene and re-evaporated to give 1-[2,3-bis(methylsulphenyl)4-chlorophenyl]-3-cyclopropyl-2-ethoxymethylenepropan-1,3-dione (4.1g) as a brown oil which was not further purified.

Workup

  1. temperatureheated
  2. temperatureat reflux for 3 hours
  3. temperatureIt was cooled
  4. customevaporated to dryness
  5. dissolutionThe residue was dissolved in toluene
  6. customre-evaporated

Sources & evidence

ORD record
ord-b894d160c7f8415d8dda08422e83e6c5
Source dataset
uspto-grants-1999_01
Patent number
US05856274

Reaction notes

Loading…