HCID 13323598, compound → HCID 54067045, compound

HRID 341785Notes

Reaction equation

HRID 341785 reaction equation
[CH2:1]([O:3][P:4]([CH:9]([NH:18][C:19]1[CH:24]=[CH:23][C:22]([N+:25]([O-])=O)=[CH:21][N:20]=1)[P:10](=[O:17])([O:14][CH2:15][CH3:16])[O:11][CH2:12][CH3:13])(=[O:8])[O:5][CH2:6][CH3:7])[CH3:2]>[Pd].C(O)C>[CH2:12]([O:11][P:10]([CH:9]([NH:18][C:19]1[CH:24]=[CH:23][C:22]([NH2:25])=[CH:21][N:20]=1)[P:4](=[O:8])([O:3][CH2:1][CH3:2])[O:5][CH2:6][CH3:7])(=[O:17])[O:14][CH2:15][CH3:16])[CH3:13]

Participants

4

Reactant 1

HCID 13323598HCID 13323598, compound

Product 1

HCID 54067045HCID 54067045, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

[(5-Nitro-2-pyridinyl)aminomethylene]bis[phosphonic acid] tetraethyl ester (5.29 9, 12.4 mmol), absolute ethanol (100 ml) and 10% palladium on charcoal (1.3 g) are placed in a 500 ml Parr hydrogenation flask and hydrogenated for 4 hours at 40 psi. The reaction mixture is filtered through celite then concentrated under reduced pressure. The resultant solid is carried on without further purification.

Workup

  1. filtrationThe reaction mixture is filtered through celite
  2. concentrationthen concentrated under reduced pressure
  3. customThe resultant solid is carried on without further purification

Sources & evidence

ORD record
ord-e8b97391e2ca4e758776dd494fc128db
Source dataset
uspto-grants-1999_01
Patent number
US05856314

Reaction notes

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