Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Piperidineethanol → benzyl N-[4-(2-hydroxyethyl)piperidine-1-carboximidoyl]carbamate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Piperidineethanol | HCID 73953 | — |
| 반응물 | Benzyl [amino(methylsulfanyl)methylene]carbamate | HCID 140362141 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | benzyl N-[4-(2-hydroxyethyl)piperidine-1-carboximidoyl]carbamate | HCID 140379078 | 41% |
반응 단계
A mixture of 6.2 g (0.028 mol) of 4-hydroxyethyl piperidine and 3.6 g (0.028 mol) of N-benzyloxycarbonyl-S-methyl isothiourea in 50 ml of acetonitrile was refluxed overnight. Evaporation and flash chromatography on silica gel with ethyl acetate gave 3.5 g (41%) of the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05856307 |
| 출처 데이터셋 | uspto-grants-1999_01 |
| ORD ID | ord-353250c9f0ee4df5a9503355158e2cd7 |
| 출처 메모 | uspto-grants-1999_01 |