Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 34181Generated: October 26, 2026

Diisopropylethylamine → HCID 178470920, compound

https://huagongshe.com/reaction/34181

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
ReactantEthyl 3-(piperidin-2-YL)propanoateHCID 436982—
ReactantPentafluorphenol-tetramethyluronium hexafluorophosphatHCID 15840204—
Reactant6-chloro-4-(1-(5-chloro-1H-benzimidazol-2-yl)-ethylamino]-7-hydroxycarbonyl-quinazolineHCID 178463504—
SolventDimethyl SulfoxideHCID 679—
ProductHCID 178470920HCID 178470920—

Reaction Steps

Prepared analogously to Example 37a from 6-chloro-4-[1-(5-chloro-1H-benzimidazol-2-yl)-ethylamino]-7-hydroxycarbonyl-quinazoline, pentafluorophenyl-tetramethyluronium-hexafluorophosphate (PFTU), diisopropylethylamine and ethyl 3-piperidin-2-yl-propionate in DMSO at ambient temperature.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429597B2
Source datasetuspto-grants-2008_09
ORD IDord-08afb61f6d6344a590bcb31e32316170
Source noteuspto-grants-2008_09