反应详情

A portion (0.2 g) of 5,6-dihydro-2-(2-phenylethyl)-4H-imidazo[4,5,1-ij]quinolin-6-ol obtained in Example 4 was dissolved in ether (10 mL) and dichloromethane (10 mL); following the addition of 10% HCl-methanol solution (0.5 g), the solvents were removed under reduced pressure, followed by crystallization from ether; upon filtration, the titled compound was obtained as colorless crystals (0.23 g).

1. customthe solvents were removed under reduced pressure
2. customfollowed by crystallization from ether
3. filtrationupon filtration