HRID341941

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCCO[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1n1ccc(NC(=O)c2ccccc2)nc1=O

HCID22874774

未命名化合物

结构：COc1cccc(C(Cl)(c2ccccc2)c2ccccc2)c1OC

HCID66624882

未命名化合物

PRODUCTS

生成物

结构：CCCO[C@@H]1[C@H](O)[C@@H](COC(c2ccccc2)(c2ccccc2)c2cccc(OC)c2OC)O[C@H]1n1ccc(NC(=O)c2ccccc2)nc1=O

HCID69941629

未命名化合物

收率 49%

PROCEDURE

实验过程

N4-Benzoyl-2'-O-propylcytidine (3.0 g, 0.007 mol) was treated with dimethoxytrityl chloride (1.5 g) as per the procedure of Example 72 to give 1.5 g of pure product. Anal. Calcd. for C40H42N3O8. 1/2H2O: C, 68.45; H, 6.18; N, 5.99. Found: C, 68.39; H, 5.99; N, 5.95.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a3b5fbaaa37249e29adc26e77979e95a
来源数据集: uspto-grants-1999_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05856466
来源说明: uspto-grants-1999_01

反应 SMILES

[C:1]([NH:9][C:10]1[CH:27]=[CH:26][N:13]([C@@H:14]2[O:25][C@H:22]([CH2:23][OH:24])[C@@H:20]([OH:21])[C@H:15]2[O:16][CH2:17][CH2:18][CH3:19])[C:12](=[O:28])[N:11]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:29][O:30][C:31]1[C:32]([O:51][CH3:52])=[C:33]([CH:48]=[CH:49][CH:50]=1)[C:34](Cl)([C:41]1[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=1)[C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1>>[C:1]([NH:9][C:10]1[CH:27]=[CH:26][N:13]([C@@H:14]2[O:25][C@H:22]([CH2:23][O:24][C:34]([C:41]3[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=3)([C:35]3[CH:36]=[CH:37][CH:38]=[CH:39][CH:40]=3)[C:33]3[CH:48]=[CH:49][CH:50]=[C:31]([O:30][CH3:29])[C:32]=3[O:51][CH3:52])[C@@H:20]([OH:21])[C@H:15]2[O:16][CH2:17][CH2:18][CH3:19])[C:12](=[O:28])[N:11]=1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1