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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 34195Generated: October 25, 2026

Diisopropylethylamine → HCID 178463503, compound

https://huagongshe.com/reaction/34195

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
ReactantN-MethylcyclopropanamineHCID 11029756—
ReactantPentafluorphenol-tetramethyluronium hexafluorophosphatHCID 15840204—
Reactant6-chloro-4-(1-(5-chloro-1H-benzimidazol-2-yl)-ethylamino]-7-hydroxycarbonyl-quinazolineHCID 178463504—
SolventDimethyl SulfoxideHCID 679—
ProductHCID 178463503HCID 178463503—

Reaction Steps

Prepared analogously to Example 37a from 6-chloro-4-[1-(5-chloro-1H-benzimidazol-2-yl)-ethylamino]-7-hydroxycarbonyl-quinazoline, pentafluorophenyl-tetramethyluronium-hexafluorophosphate (PFTU), diisopropylethylamine and N-cyclopropyl-methylamine in DMSO at ambient temperature.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429597B2
Source datasetuspto-grants-2008_09
ORD IDord-c9b85443dce94bf585d06e27ab47e1be
Source noteuspto-grants-2008_09