HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → methyl 3-(R)-hydroxy-2-(S)-methylbutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Methyl 3-hydroxybutyrate, (R)- | HCID 2724279 | — |
| Product | methyl 3-(R)-hydroxy-2-(S)-methylbutanoate | HCID 11126297 | — |
Reaction Steps
This compound was prepared according to the procedure of Example 127, but the methyl 3-(R)-hydroxybutanoate was first alkylated with methyl iodide as described by Keck et al., (J. Org. Chem., 1985, 4317) to give methyl 3-(R)-hydroxy-2-(S)-methylbutanoate. The latter was transformed into the thiol according to the procedure of Example 127.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05856322 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-6c6f285415f64e4e8160110e7519a229 |
| Source note | uspto-grants-1999_01 |