HCID 15326267, compound → 3-[2-(N,N-Dimethylamino)ethyl]-5-vinyl-1H-indole

HRID 342028Notes

Reaction equation

HRID 342028 reaction equation
[CH3:1][N:2]1[CH2:6]C[CH:4]([C:7]2[C:15]3[C:10](=[CH:11][CH:12]=[C:13]([CH:16]=[CH2:17])[CH:14]=3)[NH:9][CH:8]=2)[CH2:3]1.BrC1C=C2C(=CC=1)NC=C2C1C(=O)N(C)C(=O)C1>>[CH3:1][N:2]([CH2:3][CH2:4][C:7]1[C:15]2[C:10](=[CH:11][CH:12]=[C:13]([CH:16]=[CH2:17])[CH:14]=2)[NH:9][CH:8]=1)[CH3:6]

Participants

3

Reactant 2

HCID 15326267HCID 15326267, compoundHCID 19600946HCID 19600946, compound

Product 1

HCID 104432413-[2-(N,N-Dimethylamino)ethyl]-5-vinyl-1H-indole

Procedure

3-(N-Methylpyrrolidin-3-yl)-5-vinyl-1H-indole: from 3-(5-bromo-1H-indol-3-yl)-N-methylsuccinimide (Example 4) (27% over 2 steps, HRMS-FAB+ for C15H18N2 : calculated MH+ : 227.15483; found MH+ : 227.15356).

Sources & evidence

ORD record
ord-e1cd62ad06fd41d08ee04f70acd035d0
Source dataset
uspto-grants-1999_01
Patent number
US05856510

Reaction notes

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