HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 54005158, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium Cyanide | HCID 8929 | — |
| Reactant | HCID 17933665 | HCID 17933665 | — |
| Catalyst | Manganese oxide | HCID 160959 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 54005158 | HCID 54005158 | — |
Reaction Steps
30 ml of methanol, 120 ul of acetic acid, 2.25 g of manganese oxide and 300 mg of sodium cyanide are added respectively to a solution of 600 mg of the product of Example 7 in methylene chloride. The reaction medium is left under agitation at ambient temperature for 96 hours, followed by filtering, washing with ethyl acetate and evaporating. 410 mg of expected product is obtained M.p.=158° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05856509 |
| Source dataset | uspto-grants-1999_01 |
| ORD ID | ord-a59bd4e12c2d4599a1dee1e3c3126397 |
| Source note | uspto-grants-1999_01 |