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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 34205Generated: October 29, 2026

Diisopropylethylamine → HCID 178463480, compound

https://huagongshe.com/reaction/34205

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
ReactantPentafluorphenol-tetramethyluronium hexafluorophosphatHCID 15840204—
ReactantN,N-Dimethyl-1-piperidin-3-ylmethanamineHCID 16768076—
Reactant6-chloro-4-(1-(5-chloro-1H-benzimidazol-2-yl)-ethylamino]-7-hydroxycarbonyl-quinazolineHCID 178463504—
ProductHCID 178463480HCID 178463480—

Reaction Steps

Prepared analogously to Example 37a from 6-chloro-4-[1-(5-chloro-1H-benzimidazol-2-yl)-ethylamino]-7-hydroxycarbonyl-quinazoline, pentafluorophenyl-tetramethyluronium-hexafluorophosphate (PFTU), diisopropylethylamine and 3-(dimethylamino-methyl)-piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429597B2
Source datasetuspto-grants-2008_09
ORD IDord-66f12a43942a47baadb69605b1703282
Source noteuspto-grants-2008_09