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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 342068Generated: October 25, 2026

Oxalyl chloride → 3-[1-(2-propyl)-6-methoxymethyl-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione

https://huagongshe.com/reaction/342068

Reaction equation

Participants

RoleNameHCIDCharge
ReactantOxalyl chlorideHCID 65578—
ReactantIsopropyl 1-methyl-3-indoleacetimidate hydrochlorideHCID 22907276—
ReactantHCID 54229564HCID 54229564—
Product3-[1-(2-propyl)-6-methoxymethyl-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dioneHCID 17895481—

Reaction Steps

6-Methoxymethyl-1-(2-propyl)indole was reacted with oxalyl chloride and then 2-(1-methyl-1H-indol-3-yl) ethanimidic acid isopropyl ester hydrochloride as described in Example 3b to yield 3-[1-(2-propyl)-6-methoxymethyl-1H-indol-3-yl]-4-(1-methyl-1H-indol-3-yl)-pyrrole-2,5-dione.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05856517
Source datasetuspto-grants-1999_01
ORD IDord-f239dbe9b161478ebb17477ebbb2370b
Source noteuspto-grants-1999_01