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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 34209Generated: October 26, 2026

(+-)-Anabasine → HCID 178463464, compound

https://huagongshe.com/reaction/34209

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(+-)-AnabasineHCID 2181—
ReactantDiisopropylethylamineHCID 81531—
ReactantPentafluorphenol-tetramethyluronium hexafluorophosphatHCID 15840204—
Reactant6-chloro-4-(1-(5-chloro-1H-benzimidazol-2-yl)-ethylamino]-7-hydroxycarbonyl-quinazolineHCID 178463504—
SolventDimethyl SulfoxideHCID 679—
ProductHCID 178463464HCID 178463464—

Reaction Steps

Prepared analogously to Example 37a from 6-chloro-4-[1-(5-chloro-1H-benzimidazol-2-yl)-ethylamino]-7-hydroxycarbonyl-quinazoline, pentafluorophenyl-tetramethyluronium-hexafluorophosphate (PFTU), diisopropylethylamine and 2-(pyridin-3-yl)-piperidine in DMSO at ambient temperature.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07429597B2
Source datasetuspto-grants-2008_09
ORD IDord-00329d608b2442d3b6533b7485d61d9e
Source noteuspto-grants-2008_09